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KMID : 0061119820100000094
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Bulletin of the Clinical Research Institute
1982 Volume.10 No. 0 p.94 ~ p.94
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Regional Cerevral Blood Flow on Cerebral Reperfusion after Occlusion of Bilateral Common Carotic Arteries:An Experimental Cat Model
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Kang, Joon-Ki
Paik, Min-Woo/Kim, Chan-Moon/Ha, Young-Soo/Song, Jin-Un
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Abstract
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This experiment was planned to determine the effects of ischemia on subsequential regional cerebral blood flow (rCBF) and cortical electric activities following reperfusion after ischemia and also define the proper time of vascular occulsion without irreversible neural damage. The mean CBF was 24.6±7.0 ㎖/ 100 g/ min in control group. Bilateral carotid occulsion resulted in a reduction of rCBF to 50% of control flow on both hemispheres, and there was also a reduction of electrical activity in the brain. A close correlation was found between cortical electrical activity and rCBF suggesting a threshold relationship. The rCBF and cortical electric activity restored to normal states in reperfusion within 10 minutes after occulsion of both carotid arteries.
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